Rab6-interacting golgin

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August undefined, 2024

WebJan 14, 2009 · Comparison with the structure of Rab6 in complex with the human golgin protein GCC185 shows similarities in the nature of the Rab-effector interface and topology … WebFeb 1, 2009 · Interactions with Rab6 are restricted to a1 and a8 of the RUN1 domain. The intervening helix a9 (residues 919-926) ... ison with the structure of Rab6 in complex with the human golgin.

GORAB Gene - GeneCards GORAB Protein GORAB Antibody

WebHere we demonstrate that gerodermia osteodysplastica is caused by loss-of-function mutations in SCYL1BP1, which is highly expressed in skin and osteoblasts. The protein … WebApr 8, 1999 · The domain preferentially bound to Rab6 on protein blots, and mutations that abolished Golgi targeting resulted in a loss of this interaction. Sequence analysis revealed … federally incorporated company canada search

A novel Rab6-interacting domain defines a family of Golgi-targeted …

WebIn recent years, a large number of coiled-coil proteins localised to the Golgi apparatus have been identified using antisera from human patients with a variety of autoimmune … WebAug 29, 2011 · Previously, successful purification of the RUN-PLAT tandem domains (residues 683-1061) of the 1263-residue Rab6-interacting protein 1 (R6IP1) required co-expression with Rab6, as attempts to solubly express the ... Rab And Arl GTPase Family Members Cooperate in the Localization of the Golgin GCC185. Journal Article Burguete, A ... WebRAB6-interacting golgin, N-terminal kinase-like-binding protein 1, NTKL-binding protein 1, SCY1-like 1 binding protein 1, SCYL1-binding protein 1. GeneRIFs: Gene References Into Functions. GORAB promotes embryonic lung maturation through antagonizing AKT phosphorylation, versican expression, and mesenchymal cell migration. federally funded home loan

The Golgi-targeting motif of golgin, RAB6-interacting (GORAB) is …

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WebNov 1, 2024 · Second, Myosin II and RAB6 are found co-localized on peripheral dots with GCC185, a TGN Golgin known to recruit the MT + TIP CLASP proteins to the TGN, allowing the nucleation and formation of ... WebApr 8, 1999 · Interaction of golgin-97 and golgin-245 with Rab6 on farwestern blots. Golgin-97 was used to probe farwestern blots of Rab1, 2, 3a, 5, 6 and 11. (a) A quantitation of such a blot is shown together with an equivalent Coomassie-stained gel. (b) An autoradiograph of an experiment using Rab1 and Rab6 probed with golgin-97 and golgin-245. federally incorporated company searchWebco-workers, GFP-tagged Rab6 and Rab11 were shown to associate with C. trachomatis [28]. Detailed analysis demonstrated that Chlamydia expresses and secretes specific Rab binding proteins into the inclusion membrane, but the precise function of Rab interactions for Chlamydia remains elusive [29,30]. Here we show that Rab6A and Rab11A regulate ... decreased lymphocytes count

"WebJan 25, 2008 · As expected, Golgin-97 and Golgin-245 also lost Golgi association in Arl1 depleted cells , however global TGN organization remained intact as determined by TGN46 localization . Yet the Y1618A mutation did not completely abolish Golgi localization, from which we conclude that C-110 associates predominantly via Rab-binding domain … " - Rab6-interacting golgin

Rab6-interacting golgin

Gorab Mouse Gene Details golgin, RAB6-interacting

WebFeb 5, 2024 · GORAB golgin, RAB6 interacting Gene ID: 92344 ... This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase ... WebThe golgin family consists of a group of coiled-coil proteins that play different roles in Golgi-related transport processes. The GORAB protein interacts with the GTP-bound form of the …

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This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi apparatus. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it … See more RAB6-interacting golgin also known as N-terminal kinase-like-binding protein 1 (NTKL-BP1) or SCY1-like 1-binding protein 1 (SCYL1-BP1) is a protein that in humans is encoded by the GORAB gene. See more Mutations in this gene have been associated with geroderma osteodysplastica. See more • Yan J, Di Y, Shi H, Rao H, Huo K (October 2010). "Overexpression of SCYL1-BP1 stabilizes functional p53 by suppressing MDM2-mediated ubiquitination". FEBS Letters. 584 (20): … See more • Gerodermia osteodysplastica See more • SCYL1BP1+protein,+human at the U.S. National Library of Medicine Medical Subject Headings (MeSH) This article incorporates text from the United States National Library of Medicine See more WebRAB6-interacting golgin. Gene. Gorab. Status. UniProtKB reviewed (Swiss-Prot) Organism. Rattus norvegicus (Rat) Amino acids. 368. Protein existence. Evidence at transcript level. Annotation score. 3/5. Entry. Feature viewer. ... PTHR21470 RAB6-INTERACTING PROTEIN GORAB 1 hit; Pfam. View protein in Pfam;

WebMar 21, 2024 · GORAB (Golgin, RAB6 Interacting) is a Protein Coding gene. Diseases associated with GORAB include Geroderma Osteodysplasticum and Cutis Laxa, … WebPTHR21470:SF2 RAB6-INTERACTING GOLGIN 1 hit; PTHR21470 RAB6-INTERACTING PROTEIN GORAB 1 hit; Pfam. View protein in Pfam; PF04949 Transcrip_act 1 hit; MobiDB.

WebApr 8, 1999 · Interaction of golgin-97 and golgin-245 with Rab6 on farwestern blots. Golgin-97 was used to probe farwestern blots of Rab1, 2, 3a, 5, 6 and 11. (a) A quantitation of … Webgolgin, RAB6 相互作用：该基因编码 golgin 家族的一个成员，golgin 家族是一组定位于高尔基体的卷曲螺旋蛋白。编码的蛋白质可能在分泌途径中起作用。编码的蛋白质也定位于细胞质，通过与 N 末端激酶样蛋白质的相互作用而被鉴定，因此它可能在有丝分裂中发挥作用。

WebThis gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The encoded protein may function in the secretory pathway. The encoded protein, which also localizes to the cytoplasm, was identified by interactions with the N-terminal kinase-like protein, and thus it may function in mitosis. Mutations in this gene have been …

WebAug 22, 2024 · By interacting with Rab6, TMF also regulates retrograde membrane traffic from endosomes to the GA and from the Golgi to the ... SCYL1-Binding Protein 1; hNTKL-BP1; Golgin, RAB6 Interacting) GORAB is a coiled-coil membrane protein which localizes in trans-Golgi via a specific, GTP-dependent interaction with the small GTPases ARF5 and ... federally funded programsWebPR:000008148 RAB6-interacting golgin (term hierarchy) InterPro Domains. IPR007033 RAB6-interacting golgin. Molecular Reagents less. All nucleic 31. cDNA 31. Microarray … federally funded student loans navientWebFeb 8, 2024 · The activity of Vps34 in promoting autophagy depends on its interactions within a multi-protein complex including the essential mammalian autophagy protein ... federally funded nutrition programsWebNov 6, 2024 · Loss of RAB6-interacting golgin (GORAB) causes impairment of coat protein complex I (COPI)-mediated retrieval of trans-Golgi enzymes, resulting in a deficit in … federally funded medicaidWebFeb 5, 2024 · GORAB golgin, RAB6 interacting Gene ID: 92344 ... This gene encodes a member of the golgin family, a group of coiled-coil proteins localized to the Golgi. The … federally funded preschool programsWebNov 1, 2024 · Second, Myosin II and RAB6 are found co-localized on peripheral dots with GCC185, a TGN Golgin known to recruit the MT + TIP CLASP proteins to the TGN, allowing … federally incorporated companyWebDownload scientific diagram The Golgi-targeting motif of golgin, RAB6-interacting (GORAB) is found within amino acids 200 to 277 of the internal Golgi-targeting Rab6 and Arf5 binding domain ... decreased lung diffusion capacity